Drugs for cough management

SAQ/LAQ/Viva

Classify the drugs used in the management of cough.

1. Cough suppressants (Antitussives):

(a) Causing sedation: Codeine, Dextromethorphan, Pholcodeine, Levopropoxyphene

(b) Causing less sedation: Pipazethete, coramiphene, carbetapentane, Oxeladin, Chlophedianol, Noscapine

2. Expetorants (Muokinetics)

a. Mucolytics: Bromhexine, Ambroxol, Acetylcysteine, Carbocisteine

b. Drugs increasing bronchial secretions: Ammonium chloride, Potassium Iodide,  Sodium Iodide, Guaiphenesin (Glyceryl guaiacolate), Vasaka, Balsum of Tolu

c. Antihistamines: Chlorpheniramine, Diphenhydramine, Promethazine, Levocetrizine, Fexofenadine

3. Pharyngeal demulcents:(Soothening/Mucoprotective/Wetting):

Syrups, Glycerine, Linctuses, Menthol, Liquorice

4. Others: Drugs useful by other mechanisms

a. Local anesthetics: Benzonatate, Levodropropizine and Nebulised lignocaine

b. Bronchodilators: Terbutaline, Salbutamol, Levsalbutamol, Ipratropium

c.  Prokinetics: Pantoprazole, Lansoprazole, Rabeprazole

d. H2 blockers: Ranitidine, Famotidine

e. Glucocorticoids: Dexamethasone, Betamethasone, Prednisone

f. Decongestants: Phenylpropanolamine, Phenylephrine, Pseudoephedrine